One post-doc position for 24 months is available in the group coordinated by prof Annibale Puca at the IRCCS MultiMedica, Milan, Italy.
The candidate will be involved in the activities of the project financed by the italian Ministry of Health titled “The longevity-associated variant of BPIFB4: a novel tool against thrombocytosis and “aspirin resistance” in diabetes” Project code: PNRR-MAD-2022-12376723 in collaboration with the group of Dr. Gaia Spinetti – CUP I43C22000530006 legato al CUP Master del Capofila Neuromed F53C22001830006.
Position
IRCCS MultiMedica is a center of excellence for cardiovascular research and offers a highly stimulating scientific environment that supports the close interactions between basic researchers, translational researchers, and clinicians. The Institute is equipped with advanced instrumentations for biomedical research, including a flow cytometry facility (one BD FACS CantoII/3 laser, one BD FACS Fortessa x20/5 laser, and one BD FACS AriaII Cell Sorter/3 laser).
The candidate will be responsible of characterize platelet frequency and differentiation in relation to LAV-BPIFB4 genotype and/or BPIFB4 levels using cell and molecular biology methods in samples collected from a cohort of people with diabetes referring to MultiMedica Hospital in collaboration with the diabetology unit. In particular flow cytometry, ELISA, and real-time PCR will be used to assess peripheral blood circulating levels of the studied variables. Moreover, in vitro platelet and endothelial cell function will be studied in response to BPIFB4 recombinant protein and plasma from patients.
Specific requirements
Candidates should possess a Ph.D. in cardiovascular biology, molecular medicine, or associated fields,
Acquired skills in the following procedures are preferred:
- multicolor flow cytometry;
- cell culture.
The candidate should be enthusiastic about research, capable of learning new skills, and happy working both independently and in collaboration with other scientists.
Excellent communication skills (both verbal and written) in English are a prerequisite.
Offer
The successful candidate for this position will be offered a 24-month fixed term employment contract.
Applicants interested are invited to send their CVs and an endorsement letter to:
Candidates of both sexes (L.903/77) are invited to apply.
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